Rheumatoid arthritis (RA) is a chronic inflammatory condition that primarily affects the joints but can also impact other tissues and organs in the body. This autoimmune disease occurs when the immune system mistakenly targets the body’s own tissues, particularly the joints, leading to inflammation and potential joint damage. Approximately 1.5 million Americans suffer from RA.
Treatment options for rheumatoid arthritis vary and often involve a combination of medications and, in some cases, surgery. The primary goals of RA treatment are to manage pain, reduce inflammation, and prevent further joint damage.
Medications used to treat RA include Nonsteroidal Anti-Inflammatory Drugs (NSAIDs), Disease-Modifying Antirheumatic Drugs (DMARDs), immunosuppressants, and other specialized treatments. Each medication type works differently and is chosen based on the patient’s specific needs and disease severity.
DMARDs are a central part of RA treatment. These drugs not only relieve symptoms but also slow the progression of the disease. Examples of DMARDs include Methotrexate, Hydroxychloroquine, and Sulfasalazine. Sulfasalazine, for instance, is an oral medication usually started at a low dose of 500 milligrams, with the mechanism of action being the reduction of inflammation and immune system modulation.
Researchers continue to explore new and more effective treatments for RA. Emerging therapies include JAK inhibitors, BTK inhibitors, vagus nerve stimulation, stem cell therapy, and potential vaccines.
In some severe cases of RA, surgery may be necessary. Procedures such as synovectomy (removal of the inflamed joint lining) or tendon repair can help reduce pain and improve joint flexibility.
For a comprehensive list of medications used in RA treatment, visit Drugs.com. Additional information on RA drug types and their uses can be found at WebMD. To learn about the 10 commonly prescribed drugs for RA, Healthgrades provides detailed insights. Mayo Clinic offers an in-depth look at RA diagnosis and treatment options at Mayo Clinic. Healthline discusses a range of RA medications at Healthline. For information on DMARDs for RA, visit Verywell Health. Lastly, to learn about new treatments in the pipeline, check out Verywell Health.
