Rheumatoid Arthritis (RA) is an autoimmune and inflammatory disease characterized by the immune system mistakenly attacking healthy cells in the body, leading to painful swelling in affected parts, particularly the joints. This condition, primarily affecting joints in the hands, wrists, and knees, can result in severe pain, activity limitations, and disability if not managed properly. Adults with arthritis often experience higher rates of anxiety and depression and a significant consumption of prescription opioids.
In the United States, arthritis has been the leading reported cause of disability among adults for over 15 years. It was responsible for more than $300 billion in direct and indirect annual costs in 2013. The prevalence of arthritis is projected to increase by 49% from 2010-2012 to 2040. Rheumatoid arthritis, in particular, is a chronic condition that causes pain, swelling, and stiffness in several joints. Persistent inflammation over time can lead to mobility issues, fatigue, illness, and joint deformity. RA also affects the heart, lungs, eyes, and circulatory system, increasing the risk of other complications.
The global tofacitinib market, a medication used in the treatment of RA, is expected to grow significantly. From $2.43 billion in 2022, it is anticipated to reach $2.76 billion in 2023, with a compound annual growth rate (CAGR) of 13.4%. This growth indicates the increasing demand for effective RA treatments.
RA is a chronic disease affecting over 1.3 million Americans and about 1% of the global population. While the specific cause of RA is unknown and there is no known cure, it is one of the most common autoimmune disorders. Symptoms range from numbness and tingling to paralysis, caused by joint damage, the disease process itself, or medications used for treatment.
For more detailed information on Rheumatoid Arthritis, including its signs, symptoms, and complications, visit Verywell Health, WebMD, and HealthCentral. Additional statistics and research on Rheumatoid Arthritis can be found at RA Facts and Statistics.
